The NFL has released the 2022 schedule, and the excitement for the season ahead has begun. So has betting on the games, as opening Week 1 lines are now available at leading U.S. sportsbooks.
There are 11 road favorites to kick off Week 1 action. You’re forewarned to use responsible gambling when betting on NFL games and especially too many NFL road favorites.
NFL Week 1 Odds
The NFL Draft in Las Vegas drew plenty of interest, but the release of the Week 1 betting lines will have fans and bettors discussing the games for months ahead leading into opening night on Thursday, Sept. 8.
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